When the body makes its own Alpha Lipoic Acid (ALA), it synthesizes it in the cells powerhouse known as the mitochondria. Alpha Lipoic Acid is an antioxidant and it prevents reactive free radicals from damaging the cell membranes.
Alpha Lipoic Acid provides internal cell protection and external cell membrane protection against free radicals as it is both a water and a fat soluble antioxidant. Alpha Lipoic Acid is produced in our body on its own but as we get older or stressed the production level declines.
ALA provides antioxidant protection both inside and outside of cells. It also recycles other antioxidants circulating in the body, such as vitamins C, E, CoQ10 and glutathione. Evidence shows Alpha Lipoic Acid, when ingested, reduces urinary markers of oxidative stress. As such a powerful free radical-fighter, Alpha Lipoic Acid reduces oxidative damage caused in heart disease, toxin ingestion, and neurodegenerative diseases.
Evidence shows ALA ,when ingested, reduces urinary markers of oxidative stress. As such a powerful free radical-fighter, ALA reduces oxidative damage caused in heart disease, toxin ingestion, and neurodegenerative diseases.
You get a better result when ALA is consumed between 300-600mg/day although up to 1200mg/day has been used in research showing improvement in diabetic polyneuropathy.
People who are being treated for diabetes should seek advice with an allied health professional before using high doses of Alpha Lipoic Acid, since it may lower blood glucose levels. It has not been known as yet of an overdose of ALA.
Alpha Lipoic Acid contributes antioxidant protection and regeneration of serum antioxidants to counter oxidative stress. As a component of mitochondrial function, Alpha Lipoic Acid was found to alleviate age-related decline in activity of the mitochondria .
Recently a study validated the beneficial effects of Alpha Lipoic Acid and L-carnitine supplementation in raising energy production in the mitochondria and actually identified the mechanism responsible by improving specific enzymes necessary for mitochondrial function that normally declines with age.
As we get older, the brain is particularly susceptible to mitochondrial degradation. Alpha Lipoic Acid has been reported to improve enzyme activity in the brain. Alpha Lipoic Acid is also considered as a neuroprotective nutrient and was shown to have anti-inflammatory effects and improvements in spatial and temporal memory function. Another study notes ALA improved excitotoxic amino acid injury
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